Isley won the ‘Charles Wintour Most Promising Playwright Award’ at the Evening Standard Theatre Awards 2023 for their play The Swell, and was also nominated for Outstanding Achievement In An Affiliate Theatre at the 2024 Oliviers, as well as Best New Play, Best Director and Best Production at the 2023 Offies. Isley was a finalist for the 2021-22 Women’s Prize for Playwriting with Furies. Isley's play Skin A Cat was awarded Pick Of The Year at Vault Festival 2016 and nominated for four Off West End Awards (Most Promising New Playwright - shortlist, Best New Play, Best Lead Female, Best Director) for its transfer as inaugural production at The Bunker, 2016, then touring nationally throughout 2018. Isley won the 2025 Imison Award for Tether, was the 2014 Script6 winner at The Space with Bright Nights, received Special Commendation from the 2012 Soho Young Writers Award for Lomography, and their monologue What's So Special was performed as part of The Get Out at The Royal Court Jerwood Theatre Upstairs (2014). They were twice named Champion of Literary Death Match (Norfolk and Norwich Festival and The Book Club, London). Previous projects with the National Youth Theatre include The War Of The Worlds and Tiny Dancers.